New championship starts on August 23 with Shakhtar vs Metalist 1925 match at the NSC Olimpiyskiy in Kyiv. The main showdown in Ukrainian football is waiting for the fans on October 15 when Shakhtar and Dynamo will meet in Matchday 7 game. In general, 15 matchdays are planned to be played before the winter break.

Fixture schedule
Matchday 1. August 23, 2022. Shakhtar vs Metalist 1925
Matchday 2. August 28, 2022. Shakhtar vs Kryvbas
Matchday 3. September 3, 2022. Rukh vs Shakhtar
Matchday 4. September 10, 2022. Shakhtar vs Chornomorets
Matchday 5. October 1, 2022. Metalist vs Shakhtar
Matchday 6. October 8, 2022. Lviv vs Shakhtar
Matchday 7. October 15, 2022. Shakhtar vs Dynamo
Matchday 8. October 19, 2022. Shakhtar vs Kolos
Matchday 9. October 22, 2022. Minaj vs Shakhtar
Matchday 10. October 29, 2022. Shakhtar vs Oleksandriia
Matchday 11. November 5, 2022. Shakhtar vs Inhulets
Matchday 12. November 9, 2022. Veres vs Shakhtar
Matchday 13. November 13, 2022. Shakhtar vs Zorya
Matchday 14. November 19, 2022. Shakhtar vs Dnipro-1
Matchday 15. November 26, 2022. Shakhtar vs Vorskla

Matchday 16. May 4, 2023. Metalist 1925 vs Shakhtar
Matchday 17. May 11, 2023. Kryvbas vs Shakhtar
Matchday 18. May 18, 2023. Shakhtar vs Rukh
Matchday 19. April 1, 2023. Chornomorets vs Shakhtar
Matchday 20. April 8, 2023. Shakhtar vs Metalist
Matchday 21. April 15, 2023. Shakhtar vs Lviv
Matchday 22. April 22, 2023. Dynamo vs Shakhtar
Matchday 23. April 29, 2023. Kolos vs Shakhtar
Matchday 24. May 3, 2023. Shakhtar vs Minaj
Matchday 25. May 6, 2023. Oleksandriia vs Shakhtar
Matchday 26. May 13, 2023. Inhulets vs Shakhtar
Matchday 27. May 20, 2023. Shakhtar vs Veres
Matchday 28. May 24, 2023. Zorya vs Shakhtar
Matchday 29. May 27, 2023. Shakhtar vs Dnipro-1
Matchday 30. June 3, 2023. Vorskla vs Shakhtar